GENOME-WIDE CRISPR-CAS9 SCREENS EXPOSE GENETIC VULNERABILITIES AND MECHANISMS OF TEMOZOLOMIDE SENSITIVITY IN GLIOBLASTOMA STEM CELLS

Genome-Wide CRISPR-Cas9 Screens Expose Genetic Vulnerabilities and Mechanisms of Temozolomide Sensitivity in Glioblastoma Stem Cells

Summary: BSS Hats Glioblastoma therapies have remained elusive due to limitations in understanding mechanisms of growth and survival of the tumorigenic population.Using CRISPR-Cas9 approaches in patient-derived GBM stem cells (GSCs) to interrogate function of the coding genome, we identify actionable pathways responsible for growth, which reveal th

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Development and Application of a Tandem Force Sensor

In robot teaching for contact tasks, Toy Kitchens it is necessary to not only accurately perceive the traction force exerted by hands, but also to perceive the contact force at the robot end.This paper develops a tandem force sensor to detect traction and contact forces.As a component of the tandem force sensor, a cylindrical traction force sensor

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KEJAHATAN PENISTAAN AGAMA DAN KONSEKUENSI HUKUMNYA

This study aims to analyze the regulation and enforcement of criminal law against the crime of blasphemy (religious defamation).The method used in this research is the normative method which is carried out by examining the laws and regulations that are applied to particular legal problems.The results of this study state that Indonesia recognizes re

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